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Relation between triglycerides in human skeletal muscle and serum and the fractional elimination rate of exogenous plasma triglycerides
Author(s) -
FRÖBERG S. O.,
RÖSSNER S.,
ERICSSON M.
Publication year - 1978
Publication title -
european journal of clinical investigation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.164
H-Index - 107
eISSN - 1365-2362
pISSN - 0014-2972
DOI - 10.1111/j.1365-2362.1978.tb00818.x
Subject(s) - triglyceride , medicine , endocrinology , myocardial infarction , skeletal muscle , cholesterol , chemistry
. Muscle triglycerides, serum lipid and lipo‐protein concentrations and an intravenous fat tolerance test were determined on thirteen survivors of myocardial infarction and on fourteen subjects referred to a Lipid Clinic but without myocardial infarction. The mean concentration of triglycerides in muscle and the fractional removal rate k 2 of intravenous injected Intralipid were similar in patients with and without MI. In seventeen of these subjects type IV hyperlipoproteinaemia was found. In type IV patients the muscle triglyceride concentration was twice that found in patients without hyper‐triglyceridaemia. A negative correlation between muscle triglyceride concentration and the k 2 value was found for all subjects with a correlation coefficient of —0.62 (P< 0.001). No independent correlations were found between muscle triglyceride and serum triglyceride concentration or the triglyceride concentrations of the major lipoproteins.