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Influence of Ureteral Catheter Size on Urinary Flow Rate and Glomerular Filtration Rate in the Rat
Author(s) -
Vandewalle A.,
Bonvalet J. P.
Publication year - 1976
Publication title -
european journal of clinical investigation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.164
H-Index - 107
eISSN - 1365-2362
pISSN - 0014-2972
DOI - 10.1111/j.1365-2362.1976.tb00510.x
Subject(s) - diuretic , renal function , urology , urinary system , catheter , urine flow rate , urinary flow , medicine , chemistry , endocrinology , surgery , prostate , cancer
The influence of ureteral catheter diameter on renal function was studied in rats during different diuretic states. Urinary flow rate and glomerular filtration rate were measured on each rat using ureteral catheters of two different internal diameters. In non‐diuretic rats, urinary flow rate and glomerular filtration rate did not change according to the catheter diameter. In diuretic rats, urinary flow rate was frcm 40 to 70% lower with the smaller catheter. Differences became more marked as urinary flow rate increased. Glomerular filtration rates were about 20% lower when measured with small catheters. These results clearly demonstrate that the use of small diameter ureteral catheters during diuretic states leads to a decrease in glomerular filtration rate and urinary flow rate. The results also emphasize the importance of using large diameter catheters during such experimental conditions.