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Is Phlorizin or Its Aglycon the Inhibitor of Intestinal Glucose Transport?
Author(s) -
Blum A.L.,
Haemmerli U.P.,
LorenzMeyer H.
Publication year - 1975
Publication title -
european journal of clinical investigation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.164
H-Index - 107
eISSN - 1365-2362
pISSN - 0014-2972
DOI - 10.1111/j.1365-2362.1975.tb02296.x
Subject(s) - phlorizin , lactase , biochemistry , chemistry , glucose transporter , enzyme , medicine , endocrinology , insulin
Inhibition of glucose transport by phlorizin was examined in man by perfusion of an isolated small bowel segment. Inhibition was similar in normal and lactase deficient subjects. Since the small bowel of lactase deficient subjects contains only very small amounts of phlorizin hydrolase, phlorizin and not a product of enzymatic cleavage is the inhibitor of the small intestinal glucose carrier.