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Changes of EEG and Pulmonary Venous Admixture During a Protein Load in Patients With Cirrhosis
Author(s) -
Schomerus H.,
Buchta I.,
Arndt H.
Publication year - 1975
Publication title -
european journal of clinical investigation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.164
H-Index - 107
eISSN - 1365-2362
pISSN - 0014-2972
DOI - 10.1111/j.1365-2362.1975.tb00484.x
Subject(s) - electroencephalography , cirrhosis , medicine , hyperoxia , peripheral , cardiology , venous blood , anesthesia , gastroenterology , lung , psychiatry
. 21 patients with cirrhosis of the liver and 24 control patients were studied before and after a protein load (120 g protein per day during one week). An EEG was recorded and a visual assessment of frequency pattern was performed. Venous admixture was estimated during hyperoxia. According to the EEG frequency pattern the patient group with cirrhosis was subdivided into those with EEG slowing after the protein load (n = 7) and those without (n = 14). The following results were obtained: 1) Resting arterial blood gases did not change in either group. 2) There was a significant increase of the AaDO 2 (difference between alveolar pO 2 and peripheral arterial pO 2 ) in cirrhotics and controls. 3) The increase in AaDO 2 was significantly larger in those cirrhotics showing EEG slowing compared to those without EEG ‐ slowing or to the controls. 4) Fractional venous admixture increased significantly in those cirrhotics showing EEG slowing. There was no significant change in those patients who did not show EEG changes or in the controls.