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A Specialized Membrane Junction between Nerve Endings and B‐Cells in Islets of Langerhans
Author(s) -
Orci L.,
Perrelet A.,
Ravazzola M.,
MalaisseLagae F.,
Renold A. E.
Publication year - 1973
Publication title -
european journal of clinical investigation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.164
H-Index - 107
eISSN - 1365-2362
pISSN - 0014-2972
DOI - 10.1111/j.1365-2362.1973.tb02212.x
Subject(s) - free nerve ending , extracellular , gap junction , nerve cells , chemistry , synaptic membrane , biophysics , microbiology and biotechnology , membrane , anatomy , neuroscience , biology , intracellular , biochemistry
. The use of lanthanum as an extracellular tracer in isolated islets of Langerhans reveals zones of narrowing of the extracellular space (synaptic cleft) between nerve endings and B‐cells. These narrowed zones are interpreted as gap junctions and their presence shows that such endings have the morphological characteristics of both electrical and chemical synapses.