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Mono‐ and Divalent Electrolyte Patterns, pCO 2 and pH in Relation to Flow Rate in Normal Human Parotid Saliva *
Author(s) -
Kreusser W.,
Heidland A.,
Hennemann H.,
Wigand M. E.,
Knauf H.
Publication year - 1972
Publication title -
european journal of clinical investigation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.164
H-Index - 107
eISSN - 1365-2362
pISSN - 0014-2972
DOI - 10.1111/j.1365-2362.1972.tb00668.x
Subject(s) - chemistry , bicarbonate , electrolyte , potassium , sodium , saliva , magnesium , medicine , calcium , endocrinology , phosphate , pilocarpine , divalent , biochemistry , organic chemistry , electrode , epilepsy , psychiatry
In parotid saliva of normal subjects the pH, pCO 2 and concentrations of sodium, potassium, calcium, magnesium, bicarbonate and inorganic phosphate were determined continuously after stimulation of salivary secretion by pilocarpine. The electrolyte concentrations showed a marked dependence on salivary flow rate. Sodium, calcium and bicarbonate concentrations and pH increased with increasing flow rate but the concentrations of potassium, magnesium and inorganic phosphate decreased with increasing flow rate. In general salivary electrolyte concentrations showed a tendency to approach plasma concentrations with increasing flow rate with the exception of the salivary magnesium concentration, which fell below its plasma level and bicarbonate which exceeded the plasma concentration. The results will be considered as a basis of further investigations on electrolyte excretion patterns in patients with hormonal and metabolic disturbances.