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The prevention of hair loss from chemotherapy by the use of cold‐air scalp‐cooling
Author(s) -
ADAMS LYNN,
LAWSON NORA,
MAXTED K.J.,
SYMONDS R. P.
Publication year - 1992
Publication title -
european journal of cancer care
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.849
H-Index - 67
eISSN - 1365-2354
pISSN - 0961-5423
DOI - 10.1111/j.1365-2354.1992.tb00140.x
Subject(s) - epirubicin , medicine , hair loss , scalp , chemotherapy , anthracycline , breast cancer , dermatology , surgery , cancer , cyclophosphamide
The use of a cold‐air scalp‐cooling system to prevent alopecia following administration of anthracycline chemotherapy is described. The unit used is mounted on a four‐wheeled trolley and is highly mobile. Twenty‐four patients with advanced breast cancer received epirubicin chemotherapy, 14 at a dose of 50 mg/m 2 , and 10 at a dose of 100 mg/m 2 . All 10 patients receiving 100 mg/m 2 developed total alopecia; by contrast, only two out of 14 receiving 50 mg/m 2 had alopecia, while the remaining 12 retained their hair. Patients not receiving scalp‐cooling inevitably developed total alopecia after three pulses of epirubicin.