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ATYPICAL GLANDULAR CELLS ON SMEAR – AGE RELATED IMPLICATIONS AND MANAGEMENT
Author(s) -
Tan L.,
McCarthy J.,
Lyons D.
Publication year - 2006
Publication title -
cytopathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.512
H-Index - 48
eISSN - 1365-2303
pISSN - 0956-5507
DOI - 10.1111/j.1365-2303.2006.00392_13_27.x
Subject(s) - medicine , malignancy , incidence (geometry) , age groups , cytology , gynecology , pathology , demography , physics , sociology , optics
Atypical glandular cells on smear constitute 0.05–0.1% of all smears. The incidence appears to be rising and presents a diagnostic dilemma. The aim of our study was to assess the impact of age on disease distribution and management options. Methods: All patients presenting with atypical glandular cells on smear from January 2000 to December 2004 were analysed. All these smears were conventional smears (none LBC). Smear suggesting borderline changes in glandular cells were not included. We analysed the histopathological outcomes in patients with reference to age. Two groups were taken (a) Patients 36 years old. These age groups were taken as per BSCCP Guidelines, patients 36 years olds (2 cm deep). Results: A total of 75 women were referred, 49 women > 36 years old, 26 women were 36 years old. 3/49 patients >36 years old showed no evidence of malignancy on further testing whereas 34% showed no evidence of malignancy in patients 36 years old. Conclusions: This study suggests that ladies > 36 years old should have investigations to exclude extrauterine pathology whereas in ladies