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10 YEAR AUDIT OF GLANDULAR CYTOLOGY REPORTS WITH SPECIAL REGARD TO THE EFFECT OF CONVERSION TO LBC
Author(s) -
Shore E.,
Ash A.,
Smith J. H. F.
Publication year - 2006
Publication title -
cytopathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.512
H-Index - 48
eISSN - 1365-2303
pISSN - 0956-5507
DOI - 10.1111/j.1365-2303.2006.00392_10_1.x
Subject(s) - cytopathology , medicine , cytology , liquid based cytology , gynecology , cervical intraepithelial neoplasia , pathology , cervical cancer , cancer
Recent reviews of glandular reports have confirmed a wide variation in specificity. 1–3 We have reviewed our performance over the last 10 years and evaluated the effect of conversion to Liquid Based Cytology (LBC) on our reporting rates and accuracy. Audit revealed an upward trend in ability to accurately detect glandular lesions, with particular improvement in identification of Cervical Glandular Intraepithelial Neoplasia (CGIN).Year 1996 1997 1998 1999 2000 2001 2002 2003 2004 2005Cases reported As? glandular neoplasia 39 26 18 27 28 16 22 12 23 29 PPV for any % significant pathology 51 58 83 78 50 63 59 92 78 93 PPV for correctly identified lesion % 21 42 67 56 36 50 41 83 78 83Reasons for this general increase will be discussed, including changes to the laboratory staffing structure and better recognition of such lesions through improved training. In addition, the recent introduction of LBC technology may have resulted in improved sampling of the endocervical component through use of the Cervex Broom and smear taker training. In addition SurePath™ cell collection techniques with enhanced preservation of morphology may have lead to better recognition. References: 1. Mathers et al Cytopathology 2002, 13, 83–91 2. Pisal et al Eur J Obstet Gynaecol Reprod Biol 2003, 108, 209–212 3. Kirwan et al Cytopathology 2004, 15, 188–194