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Intraoperative cytology of clear cell carcinoma of the ovary
Author(s) -
VrdoljakMozetič D.,
Stanković T.,
Krašević M.,
VeršaOstojić D.,
ŠtembergerPapić S.,
Rupčić S.
Publication year - 2006
Publication title -
cytopathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.512
H-Index - 48
eISSN - 1365-2303
pISSN - 0956-5507
DOI - 10.1111/j.1365-2303.2006.00373.x
Subject(s) - pathology , eosinophilic , ovary , cytology , hyaline , medicine , peritoneal fluid , giemsa stain , endocrinology
Objective: To describe the cytomorphology of clear cell carcinoma (CCC) of the ovary in intraoperative samples of peritoneal fluid, imprint and scraping samples of the tumour tissue. Study design: Fourteen histologically confirmed cases, stained by standard cytological procedures, were analysed by light microscopy. Results: In 33.3% of peritoneal fluid samples and 92.9% of imprint and scraping cytological samples, besides variable clear cell cellular morphology, one or both distinct cytological characteristics were observed: eosinophilic, hyaline, extracellular, globular substance with or without formation of a ‘raspberry’ body and an eosinophilic, intracytoplasmic inclusions. These structures were clearly seen only in samples stained by May‐Grünwald–Giemsa. Conclusion: Using cytological analysis of imprint and scraping samples of ovarian tumours it is possible to make a precise intraoperative cytological diagnosis in most cases of CCC of the ovary.