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Cytologic changes induced by 131 I in the thyroid glands of patients with hyperthyroidism; results of fine needle aspiration cytology
Author(s) -
OZ F.,
URGANCIOGLU I.,
USLU I.,
DERVISOGLU S.,
OZ B.,
KANMAZ B.
Publication year - 1994
Publication title -
cytopathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.512
H-Index - 48
eISSN - 1365-2303
pISSN - 0956-5507
DOI - 10.1111/j.1365-2303.1994.tb00411.x
Subject(s) - medicine , cytology , thyroid , euthyroid , fine needle aspiration , pathology , thyroid nodules , fine needle aspiration cytology , gastroenterology , biopsy
Cytological changes in the thyroid glands of 120 patients who had received 131 I treatment for hyperthyroidism were examined in detail. the cytological material was obtained by fine needle aspiration cytology. the patients were divided into four groups according to the amount of time elapsed after the 131 I treatment. the control groups were selected from euthyroid patients with hypoactive or non‐functional solitary nodules and patients with Graves’disease who had not received 131 I therapy. the thyrocytes revealed degenerative changes in the immediate period after cessation of treatment. One year after the treatment some non‐specific changes, such as oxyphilic metaplasia and regeneration, were seen. No malignant change has been observed clinically or cytologically during up to 20 years of follow up since receiving 131 I.