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Out‐Patient Peritoneal Lavage Cytology In the Detection of Residual Epithelial Ovarian Cancer
Author(s) -
REDMAN C. W. E.,
CHAPMAN S. E.,
CHAN S. Y.,
BUXTON E. J.,
BLACKLEDGE G.,
LUESLEY D. M.
Publication year - 1991
Publication title -
cytopathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.512
H-Index - 48
eISSN - 1365-2303
pISSN - 0956-5507
DOI - 10.1111/j.1365-2303.1991.tb00503.x
Subject(s) - medicine , cytology , peritoneal fluid , epithelial ovarian cancer , ovarian cancer , pathology , minimal residual disease , cancer , bone marrow
Peritoneal lavage fluid cytology was performed in 87 out‐patients with histologically proven epithelial ovarian cancer undergoing primary management. A total of 246 peritoneal lavages were attempted, usually with temporary cannulae ( n = 229). From these, 184 samples were obtained, of which 156 (85%) were suitable for cytological analysis. the sensitivity of peritoneal lavage fluid cytology in 67 patients with known residual disease was 57% whereas serum CA 125 levels were elevated in 58 (87%). Pre‐ and post‐treatment peritoneal lavage fluid cytology had prognostic value, but this was less than that of serum CA 125 measurements.