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Functional immunocytopathology and the diagnosis of bone marrow micrometastases
Author(s) -
NEVILLE A. MUNRO
Publication year - 1990
Publication title -
cytopathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.512
H-Index - 48
eISSN - 1365-2303
pISSN - 0956-5507
DOI - 10.1111/j.1365-2303.1990.tb00351.x
Subject(s) - cytopathology , medicine , bone marrow , pathology , polymerase chain reaction , cytology , biology , gene , biochemistry
Immunocytochemical methods offer a new dimension for cytopathology in the diagnosis, prognosis and biology of neoplastic diseases. This concept is illustrated with particular respect to the immunodetection of bone marrow micrometastases and the role of cytologically demonstrable functional parameters in prognosis and therapy planning. A future role for the polymerase chain reaction (PCR) in this diagnostic sphere is proposed.