The relationship between impaired fasting glucose and self‐reported sleep quality in a C hinese population

Summary Objective Decreased sleep quality and duration predicts the development of type 2 diabetes. Prediabetes is an established risk factor for type 2 diabetes and cardiovascular disease. However, there is limited research on the association between prediabetes and sleep quality. The aim of this study is to investigate this relationship in a C hinese population. Methods Subjects were recruited from the P revention H ealth C enter of N ational C heng K ung U niversity H ospital. Anthropometric data and metabolic parameters were measured. The diagnoses of impaired fasting glucose ( IFG ), impaired glucose tolerance ( IGT ) and diabetes followed the recommendations of the A merican D iabetes A ssociation. Sleep quality was assessed using the P ittsburgh S leep Q uality I ndex ( PSQI ). Results A total of 1805 subjects with normal glucose tolerance ( NGT , n  = 1217), IFG ( n  = 118), IGT ( n  = 287), IFG + IGT ( n  = 80) and newly diagnosed diabetes ( NDD , n  = 103) were recruited. The global PSQI scores were 6·07 ± 2·44, 6·74 ± 3·23, 6·91 ± 3·51, 6·74 ± 2·26 and 7·16 ± 3·49 in subjects with NGT , IFG , IGT , IFG + IGT and NDD , respectively. Multivariate linear regression analysis showed that female gender, smoking, IGT , IFG + IGT and NDD , but not IFG , were independent determinants of global PSQI score. Multivariate logistic regression analysis showed that female gender, IGT , IFG + IGT and NDD , but not IFG , were predictors of poor sleepers. Conclusions Subjects with prediabetes and NDD had a significantly higher global PSQI score than those with NGT . Furthermore, female gender, smoking, IGT , IFG + IGT and NDD , but not IFG , were significantly associated with poor sleep quality independent of cardiometabolic risk factors in a C hinese population.