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What is active acromegaly and which parameters do we have?
Author(s) -
Neggers S. J. C. M. M.,
Biermasz N. R.,
Lely A. J.
Publication year - 2012
Publication title -
clinical endocrinology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.055
H-Index - 147
eISSN - 1365-2265
pISSN - 0300-0664
DOI - 10.1111/j.1365-2265.2012.04346.x
Subject(s) - acromegaly , medicine , endocrinology , growth hormone , insulin like growth factor , disease , hormone , growth factor , receptor
Summary Disease activity of acromegaly can be measured in many ways. Growth hormone ( GH ) and insulin‐like growth factor 1 ( IGF 1) concentrations are the main biochemical markers used to measure the response to treatment. Both GH and IGF 1 have been associated with prognosis, in particular mortality. In this review, we discuss the available parameters to assess disease activity in acromegaly.