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What medical options should be considered for the treatment of primary hyperparathyroidism?
Author(s) -
Horwitz Mara J.
Publication year - 2011
Publication title -
clinical endocrinology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.055
H-Index - 147
eISSN - 1365-2265
pISSN - 0300-0664
DOI - 10.1111/j.1365-2265.2011.04050.x
Subject(s) - parathyroidectomy , medicine , primary hyperparathyroidism , hypercalcaemia , asymptomatic , hyperparathyroidism , parathyroid hormone , endocrine system , endocrine disease , disease , vitamin d and neurology , surgery , pediatrics , hormone , calcium
Summary Primary hyperparathyroidism (PHPT) is a common, often asymptomatic, endocrine disorder characterized by hypercalcaemia in the face of a nonsuppressed parathyroid hormone (PTH) level. For those with symptomatic disease or who meet surgical criteria, parathyroidectomy is the treatment of choice. However, those patients who do not meet surgical criteria or who cannot undergo or refuse surgery must be managed medically. Medical management of PHPT involves continual assessment to determine who will benefit from surgical intervention, replacement of vitamin D, treatment of parathyroid bone disease and management of hypercalcaemia and renal stone disease.