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Acromegaly and its treatment in the McCune‐Albright syndrome
Author(s) -
Premawardhana L. D. K. E.,
Vora J. P.,
Mills R.,
Scanion M. F.
Publication year - 1992
Publication title -
clinical endocrinology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.055
H-Index - 147
eISSN - 1365-2265
pISSN - 0300-0664
DOI - 10.1111/j.1365-2265.1992.tb02272.x
Subject(s) - mccune–albright syndrome , polyostotic fibrous dysplasia , acromegaly , medicine , fibrous dysplasia , endocrine system , endocrinology , pituitary adenoma , somatostatin , adenoma , precocious puberty , pathology , growth hormone , hormone
The McCune‐Albright syndrome, comprising polyostotic fibrous dysplasia, cutaneous plgmentation and endocrine hyperfunction, is occasionally complicated by acromegaly due to a pituitary adenoma. We report a patient with the McCune‐Albright syndrome and acromegaly, who developed secondary hypothyroldism and hypoadrenalism, In whom surgical removal of the pituitary tumour was technically difficult. A combination of a long‐acting somatostatin analogue (‘Sandostatin’) and external Irradiation were therefore used as treatment.