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Pituitary–ovarian function in women with minimal or mild endometriosis and otherwise unexplained infertility
Author(s) -
Bancroft K.,
Vaughan Williams C. A.,
Elstein M.
Publication year - 1992
Publication title -
clinical endocrinology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.055
H-Index - 147
eISSN - 1365-2265
pISSN - 0300-0664
DOI - 10.1111/j.1365-2265.1992.tb00954.x
Subject(s) - unexplained infertility , infertility , endometriosis , medicine , luteal phase , endocrine system , female infertility , endocrinology , hormone , gynecology , pregnancy , biology , genetics
SUMMARY objective To determine whether abnormalities of pltuitary–ovarian function are associated with minor degrees of endometriosls in women with Otherwise unexplained infertility design Comparison of pituitary–ovarian function in a group of 22 patients with that in a control group of 10 healthy fertile women patients Twenty‐two women with minimal or miid endometrlosls and otherwise Unexplained infertility measurements Ovarian ultrasound and radloimmunoassay of pituitary and ovarian hormones results Abnormalities, including lutelnizatlon of unruptured follicles, broad LH surges and low concentrations of progesterone during the luteal phase, were demonstrated in 82% of study cycles conclusion Pituitary‐ovarian dysfunction appears to be associated with minimal or mild endometriosis in women with otherwise unexplained infertility but the diversity of endocrine abnormalities demonstrated suggests that endometriosis is unlikely to be an aetlologlcal factor in their development