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PHYSIOLOGICAL GROWTH HORMONE (GH) SECRETION DURING THE RECOVERY FROM PSYCHOSOCIAL DWARFISM: A CASE REPORT
Author(s) -
STANHOPE R.,
ADLARD P.,
HAMILL G.,
JONES J.,
SKUSE D.,
PREECE M. A.
Publication year - 1988
Publication title -
clinical endocrinology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.055
H-Index - 147
eISSN - 1365-2265
pISSN - 0300-0664
DOI - 10.1111/j.1365-2265.1988.tb03663.x
Subject(s) - dwarfism , endocrinology , medicine , secretion , growth hormone , pulse (music) , biology , psychosocial , gigantism , hormone , biochemistry , engineering , psychiatry , detector , gene , electrical engineering
SUMMARY We describe a 6.4 year old boy who had reversible GH insufficiency secondary to psychosocial dwarfism. On removal to a more favourable environment we observed the recovery of physiological GH secretion by progressive increase in GH pulse amplitude. These observations are relevant to our understanding of the control of GH secretion in that GH pulse frequency appears invariable and alteration in GH secretion is by pulse amplitude modulation.