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GROWTH HORMONE FACILITATES OVULATION INDUCTION BY GONADOTROPHINS
Author(s) -
HOMBURG R.,
ESHEL A.,
ABDALLA H. I.,
JACOBS H. S.
Publication year - 1988
Publication title -
clinical endocrinology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.055
H-Index - 147
eISSN - 1365-2265
pISSN - 0300-0664
DOI - 10.1111/j.1365-2265.1988.tb00252.x
Subject(s) - ovulation induction , medicine , menotropins , endocrinology , ovulation , hmg coa reductase , hormone , in vivo , growth hormone , biology , reductase , biochemistry , microbiology and biotechnology , enzyme
SUMMARY The addition of biosynthetic human growth hormone (GH) to treatment with human menopausal gonadotrophin (hMG) significantly augmented the ovarian response in four patients treated for in‐vivo and three patients treated for in‐vitro fertilization who had previously been resistant to hMG. The amount, duration of treatment and daily effective dose of hMG were all reduced by growth hormone. This action of growth hormone offers a new approach to ovulation induction.