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DISTURBANCES OF THE MENSTRUAL CYCLE IN BULIMIA NERVOSA
Author(s) -
PIRKE K. M.,
FICHTER M. M.,
CHLOND C.,
SCHWEIGER U.,
LAESSLE R. G.,
SCHWINGENSCHLOEGEL M.,
HOEHL C.
Publication year - 1987
Publication title -
clinical endocrinology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.055
H-Index - 147
eISSN - 1365-2265
pISSN - 0300-0664
DOI - 10.1111/j.1365-2265.1987.tb01150.x
Subject(s) - bulimia nervosa , menstrual cycle , endocrinology , medicine , anorexia nervosa , psychology , eating disorders , psychiatry , hormone
SUMMARY Blood was obtained three times a week throughout one menstrual cycle or during a 6‐week period from 15 patients with bulimia nervosa and from 10 healthy age‐matched controls. Of the patients, three had amenorrhoea, eight had oligomenorrhoea and four had regular cycles. Normal follicular development, as judged from continuously low oestradiol (E 2 ) values (<120 pg/ml or <440 pmol/1), did not occur in seven patients. Compared to patients with increasing E 2 values (> 120 pg/ml), these seven had a significantly lower body weight. Among the eight patients showing follicular development (E 2 > 120 pg/ ml), four reported regular cycles, but only three developed normal plasma progesterone (P 4 ) values during the luteal phase (P 4 > 3 ng/ml or > 9.5 nmol/1). The luteal phase was of normal length in only one bulimic patient.