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MANAGEMENT OF CRANIAL DIABETES INSIPIDUS WITH ORAL DESMOPRESSIN (DDAVP)
Author(s) -
CUNNAH D.,
ROSS G.,
BESSER G. M.
Publication year - 1986
Publication title -
clinical endocrinology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.055
H-Index - 147
eISSN - 1365-2265
pISSN - 0300-0664
DOI - 10.1111/j.1365-2265.1986.tb03265.x
Subject(s) - diabetes insipidus , desmopressin , medicine , endocrinology , nasal administration , oral administration , antidiuretic , diabetes mellitus , vasopressin , pharmacology
SUMMARY The effect of oral administration of desmopressin (DDAVP) solution was investigated in six patients with cranial diabetes insipidus of varying aetiology. All patients experienced a prompt and prolonged antidiuresis. Nine patients have been managed with oral DDAVP tablets for up to 5 months and all preferred this route of administration to intranasal application using a rhinyle. Oral DDAVP gives excellent and convenient control in cranial diabetes insipidus.