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EFFECT OF PINEALECTOMY ON SERUM MELATONIN, LUTEINIZING HORMONE AND PROLACTIN: A CASE REPORT
Author(s) -
CHIK C. L.,
TALALLA A.,
BROWN G. M.
Publication year - 1985
Publication title -
clinical endocrinology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.055
H-Index - 147
eISSN - 1365-2265
pISSN - 0300-0664
DOI - 10.1111/j.1365-2265.1985.tb01093.x
Subject(s) - pinealectomy , medicine , melatonin , endocrinology , prolactin , pineal gland , luteinizing hormone , basal (medicine) , lesion , hormone , morning , cyst , pathology , insulin
SUMMARY A patient, aged 47 is described in whom changes in hormonal profiles were observed following surgical excision of the pineal. She presented with a clinical syndrome of increased intracranial pressure and postmenopausal symptoms. Computerized tomographic scans showed obstructive hydrocephalus from a cystic lesion in the pineal region. Surgical removal of the cystic mass revealed a benign ependymal cyst and normal pineal tissue. After the operation, she had no nocturnal increase in serum melatonin. The morning basal LH was further elevated and night‐time PRL showed little fluctuation from the basal levels.