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AUTO‐IMMUNE ADDISON'S DISEASE ASSOCIATED WITH HYPERPROLACTINAEMIA
Author(s) -
LEVER E. G.,
McKERRON C. G.
Publication year - 1984
Publication title -
clinical endocrinology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.055
H-Index - 147
eISSN - 1365-2265
pISSN - 0300-0664
DOI - 10.1111/j.1365-2265.1984.tb03231.x
Subject(s) - hyperprolactinaemia , endocrinology , medicine , prolactin , addison's disease , immune system , corticosteroid , disease , hormone , immunology
SUMMARY Four cases of auto‐immune Addison's disease are reported in association with hyperprolactinaemia. Two of the females had galactorrhoea. In three cases complete resolution of hyperprolactinaemia occurred with corticosteroid replacement, but it was only partial in the fourth. We suggest that hyperprolactinaemia was due to Cortisol deficiency operating directly or indirectly at the level of the pituitary. These data support the animal and in vitro evidence for the influence of corticosteroids on prolactin release.