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CIRCANNUAL RHYTHMS OF PLASMA GROWTH HORMONE, THYROTROPIN AND THYROID HORMONES IN PREPUBERTY
Author(s) -
BELLASTELLA A.,
CRISCUOLO T.,
PERRONE A. MANGO L.,
SINISI A. A.,
FAGGIANO M.
Publication year - 1984
Publication title -
clinical endocrinology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.055
H-Index - 147
eISSN - 1365-2265
pISSN - 0300-0664
DOI - 10.1111/j.1365-2265.1984.tb00101.x
Subject(s) - prepuberty , medicine , endocrinology , hormone , thyroid hormones , thyroid , growth hormone
SUMMARY To clarify the occurrence of circannual GH, TSH, T4 and T3 rhythms in prepuberty we have been studying, for a four year period, 150 healthy subjects, aged 6–10, by cross‐sectional design. Plasma samples were taken at 0800 h and all hormones were measured by RIA. The occurrence of any circannual rhythm was statistically investigated by the cosinor method. A significant rhythm was validated ( P = 0.02) only in TSH secretion, with annual crest time in December; GH, T4, T3 did not show a circannual rhythm. Our results seem to strengthen the hypothesis that the thyroid hormones, at least before puberty, do not play an important role in the regulation of circannual TSH periodicity.