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NALOXONE INCREASES THE NICOTINE‐STIMULATED RISE OF VASOPRESSIN SECRETION IN MAN
Author(s) -
LIGHTMAN STAFFORD,
LANGDON NICOLA,
TODD KATHRYN,
FORSLING MARY
Publication year - 1982
Publication title -
clinical endocrinology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.055
H-Index - 147
eISSN - 1365-2265
pISSN - 0300-0664
DOI - 10.1111/j.1365-2265.1982.tb00727.x
Subject(s) - nicotine , vasopressin , medicine , (+) naloxone , endocrinology , antagonist , plasma osmolality , opiate , urine osmolality , secretion , saline , receptor
SUMMARY Intravenous nicotine was administered to a group of six subjects during the concurrent intravenous infusion of either the opiate antagonist naloxone, or of saline. Nicotine stimulated vasopressin secretion in all subjects. Naloxone infusion increased both the plasma vasopressin response to nicotine and the resulting rise in urine osmolality.