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THE EFFECT OF PROPRANOLOL ON THYROID HORMONES IN T3 TOXICOSIS
Author(s) -
JONES M. K.,
OWENS D. R.,
JONES G. R.,
BIRTWELL J.
Publication year - 1981
Publication title -
clinical endocrinology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.055
H-Index - 147
eISSN - 1365-2265
pISSN - 0300-0664
DOI - 10.1111/j.1365-2265.1981.tb02973.x
Subject(s) - endocrinology , propranolol , medicine , thyroid hormones , hormone , thyroid
SUMMARY Serum thyroid hormone concentrations were measured before and during 6 months treatment with propranolol (160 mg/day) in eight patients with T3 (triiodothyronine) toxicosis. Serum total T3 concentrations showed a significant ( P < 0·01) and sustained fall to approximately 80% of pre‐treatment values. Six of the patients, however, remained clinically and biochemically hyper‐ thyroid and our data do not support the use of propranolol as sole therapy in T3 toxicosis.