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METABOLIC RESPONSE TO SUBTOTAL THYROIDECTOMY IN PROPRANOLOL‐TREATED THYROTOXIC PATIENTS
Author(s) -
RASMUSSEN ULLA,
CLEMENTSEN H. J.,
JØRGENSEN J. V.,
GULDHAMMER BIRGITTE,
MOLLERUP CHARLOTTE,
KEHLET H.
Publication year - 1981
Publication title -
clinical endocrinology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.055
H-Index - 147
eISSN - 1365-2265
pISSN - 0300-0664
DOI - 10.1111/j.1365-2265.1981.tb00633.x
Subject(s) - propranolol , medicine , thyroidectomy , endocrinology , subtotal thyroidectomy , thyroid , total thyroidectomy
SUMMARY Changes in plasma cortisol, glucose, cyclic AMP, blood leucocytes, pulse rate and body temperature were measured during and for 24 h after subtotal thyroidectomy in eight propranolol‐treated (120–160 mg per day) mild to moderate thyrotoxic patients and eight patients with a non‐toxic goitre. The results showed a similar metabolic response to surgery in the two groups without any trends towards a hypermetabolic response in the toxic group. The accumulating evidence of the safety of preoperative preparation with propranolol in patients with mild to moderate thyrotoxicosis is thus supported by our results.