Premium
CORRELATIONS BETWEEN PROGESTERONE, OESTRADIOL AND ALDOSTERONE LEVELS IN THE PREMENSTRUAL SYNDROME
Author(s) -
MUNDAY MADELEINE R.,
BRUSH M. G.,
TAYLOR R. W.
Publication year - 1981
Publication title -
clinical endocrinology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.055
H-Index - 147
eISSN - 1365-2265
pISSN - 0300-0664
DOI - 10.1111/j.1365-2265.1981.tb00359.x
Subject(s) - medicine , endocrinology , radioimmunoassay , aldosterone , clinical significance , estrogen , menstrual cycle , hormone
SUMMARY Levels of progesterone, oestradiol and aldosterone in the plasma of twenty women with premenstrual syndrome (PMS) were measured by radioimmunoassay and the results were compared with those from a control series of ten normal volunteers. All the PMS patients were apparently ovulatory but the pooled progesterone values from days −9 to −5 premenstrually were significantly lower than the control values ( P < 0·05). The oestradiol levels in the PMS patients were higher than in control subjects over the last 4 days of the cycle ( P < 0·01). There was no significance in aldosterone levels between the PMS and control groups. The relevance of these results to the aetiology of PMS is considered.