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ANTIDIURETIC HORMONE IMMUNOACTIVITY IN TUMOUR TISSUE FROM PATIENTS WITH BRONCHOGENIC CARCINOMA: WITH AND WITHOUT HYPONATRAEMIA
Author(s) -
KELLY P.,
MORTON J. J.
Publication year - 1980
Publication title -
clinical endocrinology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.055
H-Index - 147
eISSN - 1365-2265
pISSN - 0300-0664
DOI - 10.1111/j.1365-2265.1980.tb03138.x
Subject(s) - antidiuretic , bronchogenic carcinoma , medicine , endocrinology , hormone , carcinoma , hyponatremia
Summary Antidiuretic hormone (ADH) immunoactivity (28–164 pg/mg wet weight) was detected in the tumour tissue of only three out of thirty‐two patients with carcinoma of the bronchus. All three patients had small oat‐cell tumours and two had persistent hyponatraemia prior to death. Serum sodium was not obtained in the third patient. Serum sodium was normal in the remaining twenty‐nine patients with undetectable ADH immunoactivity.