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DECREASED LH RESPONSE TO THE SECOND OF CONSECUTIVE DAY LUTEINIZING HORMONE RELEASING HORMONE (LHRH) INFUSIONS AMONG PATIENTS WITH CONSTITUTIONAL DELAY OF PUBERTY: A PHENOMENON OF PUBERTAL MATURATION?
Author(s) -
SCHNEIDER JILL,
LEE PETER A.
Publication year - 1980
Publication title -
clinical endocrinology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.055
H-Index - 147
eISSN - 1365-2265
pISSN - 0300-0664
DOI - 10.1111/j.1365-2265.1980.tb02737.x
Subject(s) - medicine , endocrinology , luteinizing hormone , delayed puberty , hormone , stimulation , urinary system , growth hormone
Consecutive day LHRH stimulation by continuous infusion has been used to evaluate pituitary reserve. Different responses on the 2 days were not present among non‐pubertal hypopituitary patients, pubertal growth hormone deficient patients or adult males. However, patients with constitutionally delayed puberty demonstrated a greater serum LH response on day 1 than day 2. Urinary LH responses suggest a similar but not statistically significant pattern. This response may be a normal phenomenon of puberty or may represent part of the reason for constitutionally delayed puberty.