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RESPONSE TO THYROTROPHIN RELEASING HORMONE IN KLINEFELTER'S SYNDROME
Author(s) -
YAP P. L.,
RENTON W. B.,
PRICE W. H.,
FYFFE J. A.,
LIDGARD G. P.
Publication year - 1978
Publication title -
clinical endocrinology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.055
H-Index - 147
eISSN - 1365-2265
pISSN - 0300-0664
DOI - 10.1111/j.1365-2265.1978.tb01500.x
Subject(s) - medicine , endocrinology , klinefelter syndrome , stimulation , hormone , testosterone (patch) , androgen , androgen insensitivity syndrome , thyrotropin releasing hormone , androgen receptor , cancer , prostate cancer
SUMMARY In eleven patients with Klinefelter's Syndrome TSH, T4 and T3 levels have been measured after stimulation with TRH. The eleven patients included three who had been noted to have a low radioactive iodine uptake and two of these also had abnormally low T4 levels. Three of the patients were receiving androgen replacement therapy. A normal response to TRH was observed in all cases.