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THE THYROIDAL PRODUCTION OF REVERSE TRIIODOTHYRONINE IN AUTONOMOUS ADENOMA
Author(s) -
REINWEIN D.,
DURRER H.,
EMRICH D.,
MEINHOLD H.,
WENZEL K. W.
Publication year - 1977
Publication title -
clinical endocrinology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.055
H-Index - 147
eISSN - 1365-2265
pISSN - 0300-0664
DOI - 10.1111/j.1365-2265.1977.tb01310.x
Subject(s) - diiodotyrosine , triiodothyronine , reverse triiodothyronine , medicine , endocrinology , thyroid , chemistry
SUMMARY. The ratios of reverse triiodothyronine (rT3) to triiodothyronine (T3) concentrations were similar (0.89±0.09) in twenty‐three autonomous thyroid nodules (fourteen decompensated, nine compensated) and paranodular tissues (0.82±0.08), whereas the serum ratio was significantly lower (0.098±0.014). This is compatible with the hypothesis that thyroidal rT3 and T3 production from mono‐ and di‐iodotyrosine may be a random process in contrast to non‐random extrathyroidal rT3 and T3 formation.