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EFFECT OF METOCLOPRAMIDE ON SERUM PROLACTIN LEVELS IN HUMANS
Author(s) -
DELITALA G.,
MASALA A.,
ALAGNA S.,
DEVILLA L.
Publication year - 1976
Publication title -
clinical endocrinology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.055
H-Index - 147
eISSN - 1365-2265
pISSN - 0300-0664
DOI - 10.1111/j.1365-2265.1976.tb03877.x
Subject(s) - metoclopramide , prolactin , endocrinology , medicine , hormone , vomiting
Summary The effect of acute and chronic administration of metoclopramide on serum prolactin levels in normal subjects was studied. Metoclopramide 10 mg i.v. induced a prompt rise in serum prolactin levels in all subjects. At 180 min the levels remained high. Prolactin levels were markedly elevated during a 5 day course of treatment with metoclopramide in six subjects. It is suggested that metoclopramide could be used in the functional exploration of the hypothalamic‐pituitary axis.