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FURTHER INVESTIGATIONS ON INTESTINAL HORMONAL POLYPEPTIDES
Author(s) -
MUTT VIKTOR
Publication year - 1976
Publication title -
clinical endocrinology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.055
H-Index - 147
eISSN - 1365-2265
pISSN - 0300-0664
DOI - 10.1111/j.1365-2265.1976.tb03825.x
Subject(s) - motilin , secretin , cholecystokinin , gastric inhibitory polypeptide , vasoactive intestinal peptide , pancreatic polypeptide , gastrin , hormone , gastrointestinal hormone , secretin family , endocrinology , medicine , peptide hormone , chemistry , amino acid , biology , biochemistry , secretion , neuropeptide , receptor , glucagon
SUMMARY Attempts are described to identify additional polypeptides of hormonal nature in a concentrate of intestinal polypeptides shown previously to contain secretin, cholecystokinin‐pancreozymin (CCK), motilin, gastric inhibitory polypeptide (GIP), vasoactive intestinal polypeptide (VIP), enteroglucagon and chymodenin. The probable amino acid sequence of a variant form of CCK is discolsed. The possibility of using characteristic fragments of polypeptides for the quantitation of the polypeptides themselves in crude preparations is briefly discussed.