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1‐ALPHA‐HYDROXYCHOLECALCIFEROL IN THE TREATMENT OF HYPOCALCAEMIC PSYCHOSIS
Author(s) -
GERTNER J. M.,
HODSMAN A. B.,
NEUBERGER J. N.
Publication year - 1976
Publication title -
clinical endocrinology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.055
H-Index - 147
eISSN - 1365-2265
pISSN - 0300-0664
DOI - 10.1111/j.1365-2265.1976.tb01983.x
Subject(s) - hypocalcaemia , hypoparathyroidism , alpha (finance) , medicine , endocrinology , psychosis , calcium , surgery , psychiatry , construct validity , patient satisfaction
SUMMARY Two patients with profound hypocalcaemia due to uraemia and hypopara‐thyroidism respectively presented with alterations of mental state as their dominant symptom. 1‐Alpha‐hydroxycholecalciferol (1‐α‐OHD 3 ) was chosen as the principal therapy because of its potency and rapid action. In both patients the plasma calcium was restored towards normal and the symptoms relieved within a very short period. The cases illustrate the role of 1‐α‐OHD 3 in severe hypocalcaemia due to two different causes and provide experience on which to base treatment regimes for future patients similarly afflicted.