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THE HCG STIMULATION TEST IN MEN WITH TESTICULAR DISORDERS
Author(s) -
DEKRETSER D. M.,
BURGER H. G.,
HUDSON B.,
KEOGH E. J.
Publication year - 1975
Publication title -
clinical endocrinology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.055
H-Index - 147
eISSN - 1365-2265
pISSN - 0300-0664
DOI - 10.1111/j.1365-2265.1975.tb01928.x
Subject(s) - medicine , endocrinology , leydig cell , stimulation , testosterone (patch) , sertoli cell , infertility , male infertility , spermatogenesis , hormone , biology , luteinizing hormone , pregnancy , genetics
SUMMARY The rise in plasma testosterone levels following stimulation with human chorionic gonadotrophin (3000 i.u./day for 4 days) has been used as a test of interstitial cell function in normal men and men with testicular disorders. The large majority of patients with testicular disorders resulting in infertility, showed a subnormal testosterone response to stimulation. The most marked impairment was noted in those patients with the biopsy appearance of germinal cell arrest and Sertoli cell only syndrome.