Premium
ENDOCRINE PROFILES IN PREMENSTRUAL TENSION
Author(s) -
ADAMOPOULOS D. A.,
LORAINE J. A.,
LUNN S. F.,
COPPEN A. J.,
DALY R. J.
Publication year - 1972
Publication title -
clinical endocrinology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.055
H-Index - 147
eISSN - 1365-2265
pISSN - 0300-0664
DOI - 10.1111/j.1365-2265.1972.tb00400.x
Subject(s) - pregnanediol , endocrinology , ovulation , medicine , epitestosterone , endocrine system , premenstrual tension , testosterone (patch) , anovulation , menstrual cycle , hormone , androgen , polycystic ovary , insulin resistance , insulin
SUMMARY Studies on pituitary and ovarian function as assessed by the urinary output of total gonadotrophic activity, the three classical oestrogens, pregnanediol and, in some cases, testosterone and epitestosterone, were conducted in eight patients suffering from premenstrual tension. Major abnormalities in endocrine function were not a feature of the condition. Ovulation, as judged by pregnanediol assays, was absent in seven out of the fifteen cycles investigated. Contrary to traditional belief, the symptoms of premenstrual tension could exist in the presence of cycles with anovulatory hormonal patterns.