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ACTH SECRETION BY BRONCHIAL CARCINOID TUMOURS
Author(s) -
MASON A. M. S.,
RATCLIFFE J. G.,
BUCKLE R. M.,
MASON A. STUART
Publication year - 1972
Publication title -
clinical endocrinology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.055
H-Index - 147
eISSN - 1365-2265
pISSN - 0300-0664
DOI - 10.1111/j.1365-2265.1972.tb00374.x
Subject(s) - medicine , cushing syndrome , adrenocortical carcinoma , carcinoid syndrome , lung , endocrinology , carcinoma , adrenocortical hyperfunction , pathology , hydrocortisone
SUMMARY Seven cases of adrenocortical hyperfunction associated with ACTH secreting carcinoid tumours of lung are reported. The clinical manifestations, laboratory investigations and treatment are compared with twenty‐one similar cases already recorded. The clinical picture of this disorder shows features of both pituitary dependent Cushing's syndrome and of the ectopic ACTH syndrome associated with carcinoma of lung. The problems of accurate diagnosis are described. The effects of treatment, both surgical and medical, of the adrenocortical hyperfunction are described and the problems of identifying and removing the carcinoid tumour are discussed.