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Acute myeloid leukaemia presenting as galactorrhoea
Author(s) -
MUSLAHI M. A.,
ROSS D. M.
Publication year - 2007
Publication title -
international journal of laboratory hematology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.705
H-Index - 55
eISSN - 1751-553X
pISSN - 1751-5521
DOI - 10.1111/j.1365-2257.2006.00845.x
Subject(s) - myeloid leukaemia , medicine , prolactin , hyperprolactinaemia , myeloid , presentation (obstetrics) , chemotherapy , surgery , hormone
Summary The clinical presentation of acute myeloid leukaemia is variable. We report a 40‐year‐old woman who presented with a 1‐month history of galactorrhoea with an elevated prolactin level. The blood counts were normal, but she was found to have acute myeloid leukaemia with monocytic differentiation. The serum prolactin level normalized after chemotherapy. In the absence of evidence of CNS involvement, the hyperprolactinaemia is presumed to be a paraneoplastic phenomenon. We discuss the potential mechanism of prolactin production in this case.