Miller’s seminal studies on the role of thymus in immunity | Zendy

Ribatti D. | Zendy; Crivellato E. | Zendy; Vacca A. | Zendy

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Miller’s seminal studies on the role of thymus in immunity

Author(s) -

Ribatti D.,

Crivellato E.,

Vacca A.

Publication year - 2006

Publication title -

clinical & experimental immunology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.329

H-Index - 135

eISSN - 1365-2249

pISSN - 0009-9104

DOI - 10.1111/j.1365-2249.2006.03060.x

Subject(s) - immunology , biology , miller , immunity , immune system , t lymphocyte , lymphatic system , t cell , microbiology and biotechnology , ecology

Summary The thymus is one of the two primary lymphoid organs. It is responsible for the provision of T lymphocytes to the entire body, and provides a unique microenvironment in which T cell precursors (thymocytes) undergo development, differentiation and clonal expansion. This review article summarizes the seminal work of the Australian scientist Francis Albert Pierre Miller concerning the description for the first time of the crucial role of the thymus for normal development of the immune system.

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