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Characteristics of primary cutaneous lymphoma according to WHO‐EORTC classification in Korea
Author(s) -
Lee Ji Hyun,
Lee Ji Hae,
Yoo D. S.,
Kang H.,
Kim G. M.,
Park H. J.,
Park C. J.,
Lee J. D.,
Lee J. Y.,
Kim S. Y.
Publication year - 2013
Publication title -
clinical and experimental dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.587
H-Index - 78
eISSN - 1365-2230
pISSN - 0307-6938
DOI - 10.1111/j.1365-2230.2012.04461.x
Subject(s) - medicine , lymphoma , incidence (geometry) , epidemiology , cutaneous lymphoma , lymphoproliferative disorders , cd30 , cancer , mycosis fungoides , dermatology , pathology , oncology , physics , optics
Summary Background. Primary cutaneous lymphoma (PCL) is an extranodal non‐Hodgkin lymphoma with primary involvement of the skin. Epidemiological data on PCLs according to the World Health Organization/European Organization for Research and Treatment of Cancer classification (WHO‐EORTC) has not been investigated in Korea to date. Aim. To evaluate the demographic characteristics, clinical and histological features, and survival data of patients with PCL according to the WHO‐EORTC classification. Methods. In total, 93 patients with PCL were retrospectively identified from an extensive review of medical records over a 16‐year period. Results. The tumours found included primary cutaneous CD30+ lymphoproliferative disorders, extranodal natural killer/T‐cell lymphoma and primary cutaneous diffuse large B‐cell lymphoma. We found that 81.6% of the patients had primary cutaneous T‐cell and natural killer‐cell lymphoma, and 16.2% had primary cutaneous B‐cell lymphoma, with 2.2% having precursor haematological neoplasms. The median age was 52 years (range 3–95) and the male : female ratio was 1 : 1.16. The 5‐year survival rate was 92.5%. Conclusions. The incidence rates of many PCL subtypes in Koreans differ from those of other countries.