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Systemic antifungal therapy for tinea capitis in children: a summarised Cochrane review
Author(s) -
Langowska
Publication year - 2011
Publication title -
clinical and experimental dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.587
H-Index - 78
eISSN - 1365-2230
pISSN - 0307-6938
DOI - 10.1111/j.1365-2230.2011.04190.x
Subject(s) - tinea capitis , dermatology , medicine , antifungal
Infections involving Trichophyton species Terbinafine for 4 weeks and griseofulvin for 8 weeks showed similar efficacy in 3 studies involving 382 participants (RR 1.09; 95% CI 0.95–1.26). Cure rates following treatment with itraconazole and griseofulvin for 6 weeks were similar in 1 study of 35 children (RR 1.06; 95% CI 0.81–1.39). Another study of 100 children did not show any significant difference in cure between itraconazole for 2 weeks compared with griseofulvin for 6 weeks (RR 0.89; 95% CI 0.76–1.04). There was no difference between itraconazole and terbinafine for treatment periods lasting 2–3 weeks in 2 studies involving 160 children (RR 0.93; 95% CI 0.72–1.19). Two studies that included 140 children found similar cure rates between 2–4 weeks of fluconazole with 6 weeks of griseofulvin (RR 0.92; 95% CI 0.80–1.05).