Premium
A diagnostic challenge: acute generalized exanthematous pustulosis or pustular psoriasis due to terbinafine
Author(s) -
Duckworth L.,
Maheshwari M. B.,
Thomson M. A.
Publication year - 2012
Publication title -
clinical and experimental dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.587
H-Index - 78
eISSN - 1365-2230
pISSN - 0307-6938
DOI - 10.1111/j.1365-2230.2011.04129.x
Subject(s) - acute generalized exanthematous pustulosis , terbinafine , generalized pustular psoriasis , medicine , dermatology , pustular psoriasis , psoriasis , acitretin , pustulosis , surgery , itraconazole , antifungal , osteomyelitis , osteitis
Summary A 72‐year‐old man developed a generalized erythematous pustular eruption 11 weeks after commencing terbinafine. Clinically and histologically, the appearance was that of acute generalized exanthematous pustulosis (AGEP), and the disease was managed with topical preparations. Initial improvement was marred by relapse of acute pustulosis, now more in keeping with terbinafine‐induced pustular psoriasis (PP), which was successfully treated with acitretin. This case highlights the difficulty of differentiating between AGEP and PP.