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Drug reaction with eosinophilia and systemic symptoms (DRESS): a clinical update and review of current thinking
Author(s) -
Walsh S. A.,
Creamer D.
Publication year - 2011
Publication title -
clinical and experimental dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.587
H-Index - 78
eISSN - 1365-2230
pISSN - 0307-6938
DOI - 10.1111/j.1365-2230.2010.03967.x
Subject(s) - toxic epidermal necrolysis , acute generalized exanthematous pustulosis , medicine , dermatology , eosinophilia , drug reaction , adverse drug reaction , pustulosis , drug eruption , drug , hypersensitivity reaction , intensive care medicine , immunology , psychiatry , arthritis , synovitis
Summary Drug reaction with eosinophilia and systemic symptoms (DRESS) describes a severe medication‐induced adverse reaction, which has cutaneous, haematological and solid‐organ features. It is one of the triad of life‐threatening drug hypersensitivity dermatoses, along with acute generalized exanthematous pustulosis (AGEP) and Stevens–Johnson syndrome/toxic epidermal necrolysis (SJS/TEN). In this article, we discuss several controversies that surround DRESS, including problems with nomenclature and the lack of consensus in diagnostic criteria.