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Acquired perforating dermatosis associated with pregnancy
Author(s) -
Healy R.,
Cerio R.,
Hollingsworth A.,
Bewley A.
Publication year - 2010
Publication title -
clinical and experimental dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.587
H-Index - 78
eISSN - 1365-2230
pISSN - 0307-6938
DOI - 10.1111/j.1365-2230.2009.03763.x
Subject(s) - medicine , pregnancy , elastin , pathogenesis , dermatology , diabetes mellitus , disease , systemic disease , multisystem disease , surgery , intensive care medicine , pathology , endocrinology , biology , genetics
Summary Acquired perforating collagenosis (APC) is a rare condition in which altered collagen and elastin fibres undergo transepidermal elimination. The pathogenesis is unknown but it is usually associated with underlying systemic disease, most commonly diabetes mellitus and renal impairment. We describe a case of an acquired perforating disorder occurring in pregnancy. APC is a diagnosis that can easily be missed, especially in atypical cases such as ours, and clinicians and histopathologists need to be aware of this condition to avoid unnecessary patient morbidity.