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Poromas and porokeratosis in a patient treated for solid‐organ and haematological malignancies
Author(s) -
Sherman V.,
Reed J.,
Hollowood K.,
Littlewood T.,
Burge S. M.
Publication year - 2010
Publication title -
clinical and experimental dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.587
H-Index - 78
eISSN - 1365-2230
pISSN - 0307-6938
DOI - 10.1111/j.1365-2230.2009.03751.x
Subject(s) - porokeratosis , immunosuppression , medicine , solid organ , dermatology , radiation therapy , chemotherapy , pathogenesis , disease , total body irradiation , pathology , myeloid leukaemia , organ transplantation , immunology , transplantation , cyclophosphamide
Summary We describe a patient with previous solid‐organ (testicular, oesophageal) and haematological (acute myeloid leukaemia) malignancies, in whom chronic cutaneous graft‐versus‐host disease was complicated by poromas and porokeratosis. Chemotherapy, total body irradiation, longstanding immunosuppression and ultraviolet radiation may all have played a part in the pathogenesis of the skin tumours.