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Severe exacerbation of multiple self‐healing squamous epithelioma (Ferguson–Smith disease) with radiotherapy, which was successfully treated with acitretin
Author(s) -
Robertson S. J.,
Bashir S. J.,
Pichert G.,
Robson A.,
Whittaker S.
Publication year - 2010
Publication title -
clinical and experimental dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.587
H-Index - 78
eISSN - 1365-2230
pISSN - 0307-6938
DOI - 10.1111/j.1365-2230.2009.03668.x
Subject(s) - acitretin , disfigurement , medicine , radiation therapy , basal cell , dermatology , keratoacanthoma , epidermoid carcinoma , exacerbation , surgery , pathology , psoriasis
Summary We describe the challenging case of a patient presenting with extensive, eruptive mid‐facial squamous cell carcinomas (SCCs) and keratoacanthomas (KAs) consequent to radiotherapy. Our patient had a personal and family history of multiple KAs and SCCs. Multiple self‐healing squamous epithelioma, otherwise known as Ferguson–Smith disease, was diagnosed. This case presented a therapeutic challenge to preserve tissue and avoid severe facial disfigurement. We found oral acitretin to be the treatment of choice.

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