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Multiple intravascular papillary endothelial hyperplasia affecting skin and bone
Author(s) -
Higashi Y.,
Uchida Y.,
Yoshii N.,
Kubo H.,
Kanzaki T.,
Yokouchi M.,
Kanekura T.
Publication year - 2009
Publication title -
clinical and experimental dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.587
H-Index - 78
eISSN - 1365-2230
pISSN - 0307-6938
DOI - 10.1111/j.1365-2230.2009.03459.x
Subject(s) - medicine , hyperplasia , pathology
Summary We report a 75‐year‐old man with multiple recurrent black papules involving his entire body. In the course of 3 years, 20 lesions were resected, which were histologically confirmed as intravascular papillary endothelial hyperplasia (IPEH). A similar vascular lesion was found on his tibia. The occurrence of multiple IPEH affecting skin and bone is extremely rare. The patient’s medical history included hepatitis C, hepatoma and associated coagulopathy. We suggest that this patient’s multiple lesions were induced by microthrombus formation due to liver dysfunction.