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Oesophagitis dissecans superficialis: an acute, benign phenomenon associated with pemphigus vulgaris
Author(s) -
Cesar W. G. G.,
Barrios M. M.,
Maruta C. W.,
Aoki V.,
Santi G. G.
Publication year - 2009
Publication title -
clinical and experimental dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.587
H-Index - 78
eISSN - 1365-2230
pISSN - 0307-6938
DOI - 10.1111/j.1365-2230.2009.03308.x
Subject(s) - pemphigus vulgaris , acantholysis , medicine , pemphigus , oral mucosa , dermatology , desmoglein , autoantibody , immunology , pathology , antibody
Summary Pemphigus vulgaris (PV) is an autoimmune dermatosis that may evolve to severely compromise the skin and/or mucosa. Autoantibodies directed against epithelial cadherins, such as desmogleins 1 and 3, lead to acantholysis and culminate in blister formation. Involvement of the oral mucosa is common, but other squamous stratified epithelia may also be the target of the autoimmune aggression. We report a woman with PV that was in partial remission, who developed an unusual acute phenomenon, known as oesophagitis dissecans superficialis.